Quantitative PET Reporter Gene Imaging with [11C]Trimethoprim
نویسندگان
چکیده
منابع مشابه
Quantitative PET reporter gene imaging of CD8+ T cells specific for a melanoma-expressed self-antigen
Adoptive transfer (AT) T-cell therapy provides significant clinical benefits in patients with advanced melanoma. However, approaches to non-invasively visualize the persistence of transferred T cells are lacking. We examined whether positron emission tomography (PET) can monitor the distribution of self-antigen-specific T cells engineered to express an herpes simplex virus 1 thymidine kinase (s...
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2017
ISSN: 1525-0016
DOI: 10.1016/j.ymthe.2016.10.018